human FAF1 Over-expression AAV

Name
AAV-h-FAF1

Cat No
AAV-208262

Availability
4-5 weeks

This is an AAV expressing Human FAF1.

AAV-208262

AAV-h-FAF1

Ready-to-use AAV expressing Human FAF1 (Fas associated factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CGI-03; Fas (TNFRSF6) associated factor 1; FAS-associated factor 1; hFAF1; HFAF1s; TNFRSF6-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A; UBXD12; UBXN3A

Description (eCommerce)

FAS-associated factor 1 (FAF1) binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis FAF1 requires a ubiquitin-like domain but not the FAS-binding domain [taken from NCBI Entrez Gene (Gene ID: 11124)].

Description (Vector)

Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.

Gene ID

11124

Gene Name (eCommerce)

Fas associated factor 1

Gene Name (Vector)

Fas associated factor 1

Gene Symbol

FAF1

HGNC ID

HGNC:3578

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1953

ORF Size (bp)

1953 bp

Protein Name (eCommerce)

FAS-associated factor 1

RefSeq ID

NM_007051

RefSeq Synonyms

NM_007051, BC067100, BC004970,

Research Areas

Apoptosis,CD95/FAS Signaling,Signal Transduction,TNF Signaling,Ubiquitination

Research Areas (Faceted)

cell_biology,signal_transduction

Species

human

Target Sentence

UniGene ID

Hs.530402

UniProt ID (eCommerce)

Q9UNN5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.