human FAF1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FAF1.
shADV-208262
Ad-h-FAF1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FAF1 (Fas associated factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CGI-03; Fas (TNFRSF6) associated factor 1; FAS-associated factor 1; hFAF1; HFAF1s; TNFRSF6-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A; UBXD12; UBXN3A
Description (eCommerce)
FAS-associated factor 1 (FAF1) binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis FAF1 requires a ubiquitin-like domain but not the FAS-binding domain [taken from NCBI Entrez Gene (Gene ID: 11124)].
Description (Vector)
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.
Gene ID
11124
Gene Name (eCommerce)
Fas associated factor 1
Gene Name (Vector)
Fas associated factor 1
Gene Symbol
FAF1
HGNC ID
HGNC:3578
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1953
ORF Size (bp)
1953 bp
Protein Name (eCommerce)
FAS-associated factor 1
RefSeq ID
NM_007051
RefSeq Synonyms
NM_007051, BC067100, BC004970,
Research Areas
Apoptosis,CD95/FAS Signaling,Signal Transduction,TNF Signaling,Ubiquitination
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
FAS-associated factor 1 (FAF1) binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis FAF1 requires a ubiquitin-like domain but not the FAS-binding domain [taken from NCBI Entrez Gene (Gene ID: 11124)].
UniGene ID
Hs.530402
UniProt ID (eCommerce)
Q9UNN5
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.