human EAF2 Over-expression AAV

Name 
AAV-h-EAF2
Cat No 
AAV-207506
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EAF2.

AAV-207506
AAV-h-EAF2

Ready-to-use AAV expressing Human EAF2 (ELL associated factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BM040; ELL-associated factor 2; testosterone-regulated apoptosis inducer and tumor suppressor protein; TRAITS; U19
Description (eCommerce)
ELL-associated factor 2 (EAF2) acts as a transcriptional transactivator of TCEA1 elongation activity. It is also a transcriptional transactivator of ELL (eleven nineteen lysine-rich leukemia) 1 and ELL2 elongation activities. EAF2 has been shown to be a potent inducer of apoptosis in prostatic and non-prostatic cell lines and to inhibit prostate tumor growth in vivo [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96CJ1].
Gene ID
55840
Gene Name (eCommerce)
ELL associated factor 2
Gene Name (Vector)
ELL associated factor 2
Gene Symbol
EAF2
HGNC ID
HGNC:23115
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
783
ORF Size (bp)
783 bp
Protein Name (eCommerce)
ELL-associated factor 2
RefSeq ID
NM_018456
RefSeq Synonyms
NM_018456, NM_001320041, BC014209,
Research Areas
Apoptosis,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
ELL-associated factor 2 (EAF2) acts as a transcriptional transactivator of TCEA1 elongation activity. It is also a transcriptional transactivator of ELL (eleven nineteen lysine-rich leukemia) 1 and ELL2 elongation activities. EAF2 has been shown to be a potent inducer of apoptosis in prostatic and non-prostatic cell lines and to inhibit prostate tumor growth in vivo [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96CJ1].
UniGene ID
Hs.477325
UniProt ID (eCommerce)
Q96CJ1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.