human EAF2 shRNA silencing AAV

Name
AAV-h-EAF2-shRNA

Cat No
shAAV-207506

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human EAF2.

shAAV-207506

AAV-h-EAF2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EAF2 (ELL associated factor 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BM040; ELL-associated factor 2; testosterone-regulated apoptosis inducer and tumor suppressor protein; TRAITS; U19

Description (eCommerce)

ELL-associated factor 2 (EAF2) acts as a transcriptional transactivator of TCEA1 elongation activity. It is also a transcriptional transactivator of ELL (eleven nineteen lysine-rich leukemia) 1 and ELL2 elongation activities. EAF2 has been shown to be a potent inducer of apoptosis in prostatic and non-prostatic cell lines and to inhibit prostate tumor growth in vivo [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96CJ1].

Gene ID

55840

Gene Name (eCommerce)

ELL associated factor 2

Gene Name (Vector)

ELL associated factor 2

Gene Symbol

EAF2

HGNC ID

HGNC:23115

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

783

ORF Size (bp)

783 bp

Protein Name (eCommerce)

ELL-associated factor 2

RefSeq ID

NM_018456

RefSeq Synonyms

NM_018456, NM_001320041, BC014209,

Research Areas

Apoptosis,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,transcription_translation

Species

human

Target Sentence

ELL-associated factor 2 (EAF2) acts as a transcriptional transactivator of TCEA1 elongation activity. It is also a transcriptional transactivator of ELL (eleven nineteen lysine-rich leukemia) 1 and ELL2 elongation activities. EAF2 has been shown to be a potent inducer of apoptosis in prostatic and non-prostatic cell lines and to inhibit prostate tumor growth in vivo [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96CJ1].

UniGene ID

Hs.477325

UniProt ID (eCommerce)

Q96CJ1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.