human CTNS Over-expression AAV

Name
AAV-h-CTNS

Cat No
AAV-206254

Availability
4-5 weeks

This is an AAV expressing Human CTNS.

AAV-206254

AAV-h-CTNS

Ready-to-use AAV expressing Human CTNS (cystinosin, lysosomal cystine transporter). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CTNS-LSB; PQLC4

Description (Vector)

CTNS encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

Gene ID

1497

Gene Name (Vector)

cystinosin, lysosomal cystine transporter

Gene Symbol

CTNS

HGNC ID

HGNC:2518

ORF Size (aa)

1203

ORF Size (bp)

1203 bp

RefSeq ID

NM_004937

RefSeq Synonyms

NM_004937, NM_001031681, BC032850,

Species

human

UniGene ID

Hs.187667

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.