human CTNS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CTNS.
shAAV-206254
AAV-h-CTNS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CTNS (cystinosin, lysosomal cystine transporter). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CTNS-LSB; PQLC4
Description (Vector)
CTNS encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.
Gene ID
1497
Gene Name (Vector)
cystinosin, lysosomal cystine transporter
Gene Symbol
CTNS
HGNC ID
HGNC:2518
ORF Size (aa)
1203
ORF Size (bp)
1203 bp
RefSeq ID
NM_004937
RefSeq Synonyms
NM_004937, NM_001031681, BC032850,
Species
human
UniGene ID
Hs.187667
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.