human CNOT3 Over-expression AAV

Name
AAV-h-CNOT3

Cat No
AAV-205608

Availability
4-5 weeks

This is an AAV expressing Human CNOT3.

AAV-205608

AAV-h-CNOT3

Ready-to-use AAV expressing Human CNOT3 (CCR4-NOT transcription complex subunit 3). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CCR4-associated factor 3; CCR4-NOT transcription complex subunit 3; LENG2; leukocyte receptor cluster member 2; NOT3; NOT3 (negative regulator of transcription 3, yeast) homolog; NOT3H

Description (eCommerce)

CNOT3 (CCR4-NOT transcription complex subunit 3) is a component of the CCR4-NOT core complex that functions as a general transcriptional regulator. In a genome-wide siRNA screen for genes essential for mouse embryonic stem cell self-renewal, CNOT3 was identified and found to co-occupy gene promoters with c-Myc and Zfx.

Gene ID

4849

Gene Name (eCommerce)

CCR4-NOT transcription complex subunit 3

Gene Name (Vector)

CCR4-NOT transcription complex subunit 3

Gene Symbol

CNOT3

HGNC ID

HGNC:7879

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2262

ORF Size (bp)

2262 bp

Protein Name (eCommerce)

CCR4-NOT transcription complex subunit 3

RefSeq ID

NM_014516

RefSeq Synonyms

NM_014516, BC016474,

Research Areas

Gene Expression,RNA Processing,Transcription Factor/Regulator,Translational Control

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

CNOT3 (CCR4-NOT transcription complex subunit 3) is a component of the CCR4-NOT core complex that functions as a general transcriptional regulator. In a genome-wide siRNA screen for genes essential for mouse embryonic stem cell self-renewal, CNOT3 was identified and found to co-occupy gene promoters with c-Myc and Zfx.

UniGene ID

Hs.343571

UniProt ID (eCommerce)

O75175

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.