human CNOT3 shRNA silencing AAV

Name
AAV-h-CNOT3-shRNA

Cat No
shAAV-205608

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CNOT3.

shAAV-205608

AAV-h-CNOT3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CNOT3 (CCR4-NOT transcription complex subunit 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CCR4-associated factor 3; CCR4-NOT transcription complex subunit 3; LENG2; leukocyte receptor cluster member 2; NOT3; NOT3 (negative regulator of transcription 3, yeast) homolog; NOT3H

Description (eCommerce)

CNOT3 (CCR4-NOT transcription complex subunit 3) is a component of the CCR4-NOT core complex that functions as a general transcriptional regulator. In a genome-wide siRNA screen for genes essential for mouse embryonic stem cell self-renewal, CNOT3 was identified and found to co-occupy gene promoters with c-Myc and Zfx.

Gene ID

4849

Gene Name (eCommerce)

CCR4-NOT transcription complex subunit 3

Gene Name (Vector)

CCR4-NOT transcription complex subunit 3

Gene Symbol

CNOT3

HGNC ID

HGNC:7879

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2262

ORF Size (bp)

2262 bp

Protein Name (eCommerce)

CCR4-NOT transcription complex subunit 3

RefSeq ID

NM_014516

RefSeq Synonyms

NM_014516, BC016474,

Research Areas

Gene Expression,RNA Processing,Transcription Factor/Regulator,Translational Control

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

CNOT3 (CCR4-NOT transcription complex subunit 3) is a component of the CCR4-NOT core complex that functions as a general transcriptional regulator. In a genome-wide siRNA screen for genes essential for mouse embryonic stem cell self-renewal, CNOT3 was identified and found to co-occupy gene promoters with c-Myc and Zfx.

UniGene ID

Hs.343571

UniProt ID (eCommerce)

O75175

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.