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human CHMP7 Over-expression AAV

Name 
AAV-h-CHMP7
Cat No 
AAV-205174
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CHMP7.

AAV-205174
AAV-h-CHMP7

Ready-to-use AAV expressing Human CHMP7 (charged multivesicular body protein 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
charged multivesicular body protein 7; CHMP family, member 7; chromatin-modifying protein 7
Description (eCommerce)
Charged multivesicular body protein 7 (CHMP7) is an ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase (PubMed:26040712). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed:26040712). CHMP7 plays a role in the endosomal sorting pathway (PubMed:16856878) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WUX9].
Gene ID
91782
Gene Name (eCommerce)
charged multivesicular body protein 7
Gene Name (Vector)
charged multivesicular body protein 7
Gene Symbol
CHMP7
HGNC ID
HGNC:28439
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
Protein Name (eCommerce)
Charged multivesicular body protein 7
RefSeq ID
NM_152272
RefSeq Synonyms
NM_152272, NM_001317899, BC042050, BC019110,
Research Areas
Host-Virus Interactions
Research Areas (Faceted)
infectious_disease
Species
human
Target Sentence
Charged multivesicular body protein 7 (CHMP7) is an ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase (PubMed:26040712). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed:26040712). CHMP7 plays a role in the endosomal sorting pathway (PubMed:16856878) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WUX9].
UniGene ID
Hs.5019
UniProt ID (eCommerce)
Q8WUX9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.