human CFLAR Over-expression AAV

Name 
AAV-h-CFLAR
Cat No 
AAV-205056
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CFLAR.

AAV-205056
AAV-h-CFLAR

Ready-to-use AAV expressing Human CFLAR (CASP8 and FADD like apoptosis regulator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CASH; CASP8AP1; Casper; CLARP; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT
Description (Vector)
CFLAR is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
Gene ID
8837
Gene Name (Vector)
CASP8 and FADD like apoptosis regulator
Gene Symbol
CFLAR
HGNC ID
HGNC:1876
ORF Size (aa)
1443
ORF Size (bp)
1443 bp
RefSeq ID
NM_003879
RefSeq Synonyms
NM_003879, NM_001308043, NM_001308042, NM_001202519, NM_001202518, NM_001202517, NM_001202516, NM_001202515, NM_001127184, NM_001127183, BC001602,
Species
human
UniGene ID
Hs.390736

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.