human CFLAR Over-expression AAV
This is an AAV expressing Human CFLAR.
AAV-205056
AAV-h-CFLAR
Ready-to-use AAV expressing Human CFLAR (CASP8 and FADD like apoptosis regulator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CASH; CASP8AP1; Casper; CLARP; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT
Description (Vector)
CFLAR is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
Gene ID
8837
Gene Name (Vector)
CASP8 and FADD like apoptosis regulator
Gene Symbol
CFLAR
HGNC ID
HGNC:1876
ORF Size (aa)
1443
ORF Size (bp)
1443 bp
RefSeq ID
NM_003879
RefSeq Synonyms
NM_003879, NM_001308043, NM_001308042, NM_001202519, NM_001202518, NM_001202517, NM_001202516, NM_001202515, NM_001127184, NM_001127183, BC001602,
Species
human
UniGene ID
Hs.390736
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.