human BOLA3 Over-expression AAV

Name
AAV-h-BOLA3

Cat No
AAV-202232

Availability
4-5 weeks

This is an AAV expressing Human BOLA3.

AAV-202232

AAV-h-BOLA3

Ready-to-use AAV expressing Human BOLA3 (bolA family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MMDS2

Description (Vector)

BOLA3 encodes a protein that plays an essential role in the production of iron-sulfur (Fe-S) clusters for the normal maturation of lipoate-containing 2-oxoacid dehydrogenases, and for the assembly of the mitochondrial respiratory chain complexes. Mutation in this gene has been associated with multiple mitochondrial dysfunctions syndrome-2. Two alternatively spliced transcript variants encoding different isoforms with distinct subcellular localization have been reported for this gene (PMID:21944046).

Gene ID

388962

Gene Name (Vector)

bolA family member 3

Gene Symbol

BOLA3

HGNC ID

HGNC:24415

ORF Size (aa)

321

ORF Size (bp)

321 bp

RefSeq ID

NM_212552

RefSeq Synonyms

NM_212552, NM_001035505, BC153208, BC148671,

Species

human

UniGene ID

Hs.61472

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.