human ADAM17 Over-expression AAV

Name 
AAV-h-ADAM17
Cat No 
AAV-200349
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ADAM17.

AAV-200349
AAV-h-ADAM17

Ready-to-use AAV expressing Human ADAM17 (ADAM metallopeptidase domain 17). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADAM18; CD156B; CSVP; NISBD; NISBD1; TACE
Description (Vector)
ADAM17 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
Gene ID
6868
Gene Name (Vector)
ADAM metallopeptidase domain 17
Gene Symbol
ADAM17
HGNC ID
HGNC:195
ORF Size (aa)
2475
ORF Size (bp)
2475 bp
RefSeq ID
NM_003183
RefSeq Synonyms
NM_003183, BC136783, BC062687,
Species
human
UniGene ID
Hs.404914

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.