mouse Krueppel-like factor 4 (KLF4) Adenovirus

Name 
Ad-m-KLF4
Cat No 
1791
Availability
Immediate
Categories
Adenovirus, iPS stem cell factors, Over-Expression

Klf4 of the Klf family of genes was initially identified by Yamanaka and confirmed by Jaenisch as a factor for the generation of mouse iPS cells. Klf2 and Klf4 were found to be factors capable of generating iPS cells, and related genes Klf1 and Klf5 did as well, although with reduced efficiency.

Using adenovirus to deliver these transcription factors has 2 main advantages – it does not incorporate into the targeted host and therefore avoids the potential for insertional mutagenesis, and the expression is transient for a brief amount of time in order for effective reprogramming to take place.

This adenovirus expresses mouse KLF4, and it can be used in combination with other iPSC factor for the induction of iPSC reprogramming.

1791
Ad-m-KLF4

Ready-to-use mouse Krueppel-like factor 4 (KLF4) Adenovirus. KLF4 iPS adenovirus 1791

$475.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Related Citations

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.