human Oct-4 Adenovirus
Co-expression of Oct4, Sox2, KLF4 and c-Myc (Yamanaka set) in somatic cell will lead to iPSC reprogramming. Using adenovirus to deliver these transcription factors has 2 main advantages - it does not incorporate into the targeted host and therefore avoids the potential for insertional mutagenesis, and the expression is transient for a brief amount of time in order for effective reprogramming to take place.
This adenovirus expresses human Oct4, and it can be used in combination with other iPSC factor for the induction of iPSC reprogramming.
Request a Quote
Please enter your email address and we'll be in touch with more information:
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- CMV (ubiquitous)
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
- 1x10^10 PFU/ml
- Gene Symbol
- Gene ID
- Gene Synonyms
- Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4; POU5F1