mouse c-myc Adenovirus

Name 
Ad-m-Myc
Cat No 
1790
Availability
Immediate
Categories
Adenovirus, iPS stem cell factors, Over-Expression

The Myc family of genes are proto-oncogenes implicated in cancer. Yamanaka demonstrated that c-myc is a factor implicated in the generation of mouse iPS cells. Usage of the “myc” family of genes in induction of iPS cells is troubling for the eventuality of iPS cells as clinical therapies, as 25% of mice transplanted with c-myc-induced iPS cells developed lethal teratomas. N-myc and L-myc have been identified to induce instead of c-myc with similar efficiency.

Using adenovirus to deliver these transcription factors has 2 main advantages – it does not incorporate into the targeted host and therefore avoids the potential for insertional mutagenesis, and the expression is transient for a brief amount of time in order for effective reprogramming to take place.

This adenovirus expresses mouse c-Myc, and it can be used in combination with other iPSC factor for the induction of iPSC reprogramming.

1790
Ad-m-Myc

Ready-to-use mouse c-myc Adenovirus. c-Myc myc iPS adenovirus 1790

$475.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
OVA, SERPINB14
Gene Name (eCommerce)
ovalbumin
Gene Symbol
SERPINB14
NCBI Taxonomy ID (eCommerce)
9031.0
Protein Name (eCommerce)
Ovalbumin
Target Sentence
Ovalbumin is the dominant protein found in egg whites and is often used in allergy-related studies as a means to generate an allergic reaction in patients.
UniProt ID (eCommerce)
P01012

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.