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human CLCN4 Over-expression AAV

Name 
AAV-h-CLCN4
Cat No 
AAV-205352
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CLCN4.

AAV-205352
AAV-h-CLCN4

Ready-to-use AAV expressing Human CLCN4 (chloride voltage-gated channel 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ClC-4; ClC-4A; CLC4; MRX15; MRX49
Description (Vector)
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.
Gene ID
1183
Gene Name (Vector)
chloride voltage-gated channel 4
Gene Symbol
CLCN4
HGNC ID
HGNC:2022
ORF Size (aa)
2283
ORF Size (bp)
2283 bp
RefSeq ID
NM_001830
RefSeq Synonyms
NM_001830, NM_001256944, BC130278, BC036068,
Species
human
UniGene ID
Hs.495674

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.