human CLCN4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CLCN4.
shADV-205352
Ad-h-CLCN4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CLCN4 (chloride voltage-gated channel 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ClC-4; ClC-4A; CLC4; MRX15; MRX49
Description (Vector)
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.
Gene ID
1183
Gene Name (Vector)
chloride voltage-gated channel 4
Gene Symbol
CLCN4
HGNC ID
HGNC:2022
ORF Size (aa)
2283
ORF Size (bp)
2283 bp
RefSeq ID
NM_001830
RefSeq Synonyms
NM_001830, NM_001256944, BC130278, BC036068,
Species
human
UniGene ID
Hs.495674
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.