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human CKAP2 Over-expression AAV

Name 
AAV-h-CKAP2
Cat No 
AAV-205305
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CKAP2.

AAV-205305
AAV-h-CKAP2

Ready-to-use AAV expressing Human CKAP2 (cytoskeleton associated protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CTCL tumor antigen se20-10; cytoskeleton-associated protein 2; LB1; se20-10; TMAP; tumor- and microtubule-associated protein; tumor-associated microtubule-associated protein
Description (eCommerce)
CKAP2 (cytoskeletal-associated protein 2), also known as TMAP (tumor-associated microtubule-associated protein), was identified as an mRNA up-regulated in primary human gastric cancers. It was found to localize to microtubule organizing centers and microtubules and play a role in cell division. CKAP2 is required for proper chromosome segregation and the maintenance of genomic stability. It has recently been shown to be a substrate of Cdk1-cyclinB and essential for bipolar spindle formation.
Description (Vector)
CKAP2 is a cytoskeleton-associated protein involved in mitotic progression (Seki and Fang, 2007 (PubMed 17376772)).(supplied by OMIM, Mar 2008)
Gene ID
26586
Gene Name (eCommerce)
cytoskeleton associated protein 2
Gene Name (Vector)
cytoskeleton associated protein 2
Gene Symbol
CKAP2
HGNC ID
HGNC:1990
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2049
ORF Size (bp)
2049 bp
Protein Name (eCommerce)
Cytoskeleton-associated protein 2
RefSeq ID
NM_018204
RefSeq Synonyms
NM_018204, NM_001286687, NM_001286686, NM_001098525, BC136332, BC130296,
Research Areas
Apoptosis,Cell Cycle,Cell Division,Cytoskeleton
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
CKAP2 (cytoskeletal-associated protein 2), also known as TMAP (tumor-associated microtubule-associated protein), was identified as an mRNA up-regulated in primary human gastric cancers. It was found to localize to microtubule organizing centers and microtubules and play a role in cell division. CKAP2 is required for proper chromosome segregation and the maintenance of genomic stability. It has recently been shown to be a substrate of Cdk1-cyclinB and essential for bipolar spindle formation.
UniGene ID
Hs.711762
UniProt ID (eCommerce)
Q8WWK9

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.