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human CKAP2 shRNA silencing AAV

Name 
AAV-h-CKAP2-shRNA
Cat No 
shAAV-205305
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CKAP2.

shAAV-205305
AAV-h-CKAP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CKAP2 (cytoskeleton associated protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CTCL tumor antigen se20-10; cytoskeleton-associated protein 2; LB1; se20-10; TMAP; tumor- and microtubule-associated protein; tumor-associated microtubule-associated protein
Description (eCommerce)
CKAP2 (cytoskeletal-associated protein 2), also known as TMAP (tumor-associated microtubule-associated protein), was identified as an mRNA up-regulated in primary human gastric cancers. It was found to localize to microtubule organizing centers and microtubules and play a role in cell division. CKAP2 is required for proper chromosome segregation and the maintenance of genomic stability. It has recently been shown to be a substrate of Cdk1-cyclinB and essential for bipolar spindle formation.
Description (Vector)
CKAP2 is a cytoskeleton-associated protein involved in mitotic progression (Seki and Fang, 2007 (PubMed 17376772)).(supplied by OMIM, Mar 2008)
Gene ID
26586
Gene Name (eCommerce)
cytoskeleton associated protein 2
Gene Name (Vector)
cytoskeleton associated protein 2
Gene Symbol
CKAP2
HGNC ID
HGNC:1990
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2049
ORF Size (bp)
2049 bp
Protein Name (eCommerce)
Cytoskeleton-associated protein 2
RefSeq ID
NM_018204
RefSeq Synonyms
NM_018204, NM_001286687, NM_001286686, NM_001098525, BC136332, BC130296,
Research Areas
Apoptosis,Cell Cycle,Cell Division,Cytoskeleton
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
CKAP2 (cytoskeletal-associated protein 2), also known as TMAP (tumor-associated microtubule-associated protein), was identified as an mRNA up-regulated in primary human gastric cancers. It was found to localize to microtubule organizing centers and microtubules and play a role in cell division. CKAP2 is required for proper chromosome segregation and the maintenance of genomic stability. It has recently been shown to be a substrate of Cdk1-cyclinB and essential for bipolar spindle formation.
UniGene ID
Hs.711762
UniProt ID (eCommerce)
Q8WWK9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.