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human IL17RA Over-expression AAV

Name 
AAV-h-IL17RA
Cat No 
AAV-204946
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IL17RA.

AAV-204946
AAV-h-IL17RA

Ready-to-use AAV expressing Human IL17RA (interleukin 17 receptor A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R
Description (Vector)
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
Gene ID
23765
Gene Name (Vector)
interleukin 17 receptor A
Gene Symbol
IL17RA
HGNC ID
HGNC:5985
ORF Size (aa)
2601
ORF Size (bp)
2601 bp
RefSeq ID
NM_014339
RefSeq Synonyms
NM_014339, NM_001289905, BC011624,
Species
human
UniGene ID
Hs.129751

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.