human IL17RA shRNA silencing AAV

Name
AAV-h-IL17RA-shRNA

Cat No
shAAV-204946

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human IL17RA.

shAAV-204946

AAV-h-IL17RA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IL17RA (interleukin 17 receptor A). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R

Description (Vector)

Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.

Gene ID

23765

Gene Name (Vector)

interleukin 17 receptor A

Gene Symbol

IL17RA

HGNC ID

HGNC:5985

ORF Size (aa)

2601

ORF Size (bp)

2601 bp

RefSeq ID

NM_014339

RefSeq Synonyms

NM_014339, NM_001289905, BC011624,

Species

human

UniGene ID

Hs.129751

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.