mouse KLHL20 Adenovirus

Name 
Ad-m-KLHL20
Cat No 
ADV-262906
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Klhl20.

ADV-262906
Ad-m-KLHL20

Ready-to-use Adenovirus expressing Mouse Klhl20 (kelch-like 20). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI504637; D930050H05Rik; Kleip; mKIAA4210
Description (Vector)
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases.
Gene ID
226541
Gene Name (Vector)
kelch-like 20
Gene Symbol
Klhl20
ORF Size (aa)
1815
ORF Size (bp)
1815 bp
RefSeq ID
NM_001039482
RefSeq Synonyms
NM_001039482, BC019571,
Species
mouse
UniGene ID
Mm.255165

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.