mouse CLSPN Adenovirus
This is an Adenovirus expressing Mouse Clspn.
ADV-255699
Ad-m-CLSPN
Ready-to-use Adenovirus expressing Mouse Clspn (claspin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B130025E01; C85083; E130314M08Rik
Description (Vector)
Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR-dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures and may associate with S-phase chromatin following formation of the pre-replication complex (pre-RC). This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks.
Gene ID
269582
Gene Name (Vector)
claspin
Gene Symbol
Clspn
ORF Size (aa)
3948
ORF Size (bp)
3948 bp
RefSeq ID
NM_175554
RefSeq Synonyms
NM_175554, BC050848,
Species
mouse
UniGene ID
Mm.243962
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.