human ATP1A3 Over-expression AAV

Name
AAV-h-ATP1A3

Cat No
AAV-201681

Availability
4-5 weeks

This is an AAV expressing Human ATP1A3.

AAV-201681

AAV-h-ATP1A3

Ready-to-use AAV expressing Human ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AHC2; ATP1A1; CAPOS; DYT12; RDP

Description (Vector)

ATP1A3 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

478

Gene Name (Vector)

ATPase Na+/K+ transporting subunit alpha 3

Gene Symbol

ATP1A3

HGNC ID

HGNC:801

ORF Size (aa)

3042

ORF Size (bp)

3042 bp

RefSeq ID

NM_152296

RefSeq Synonyms

NM_152296, NM_001256214, NM_001256213, BC015566, BC009394, BC009282,

Species

human

UniGene ID

Hs.515427

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.