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human FANCL Adenovirus

Name 
Ad-h-FANCL
Cat No 
ADV-227556
Availability
4-5 weeks

This is an Adenovirus expressing Human FANCL.

ADV-227556
Ad-h-FANCL

Ready-to-use Adenovirus expressing Human FANCL (Fanconi anemia complementation group L). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FAAP43; PHF9; POG
Description (Vector)
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.
Gene ID
55120
Gene Name (Vector)
Fanconi anemia complementation group L
Gene Symbol
FANCL
HGNC ID
HGNC:20748
ORF Size (aa)
1128
RefSeq ID
NM_018062
RefSeq Synonyms
NM_018062, NM_001114636, BC054517, BC009042,
Species
human
UniGene ID
Hs.631890

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.