human LRP5 Adenovirus

Name
Ad-h-LRP5

Cat No
ADV-214503

Availability
4-5 weeks

This is an Adenovirus expressing Human LRP5.

ADV-214503

Ad-h-LRP5

Ready-to-use Adenovirus expressing Human LRP5 (LDL receptor related protein 5). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

BMND1; EVR1; EVR4; HBM; LR3; LRP-5; LRP7; OPPG; OPS; OPTA1; VBCH2

Description (Vector)

LRP5 encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Gene ID

4041

Gene Name (Vector)

LDL receptor related protein 5

Gene Symbol

LRP5

HGNC ID

HGNC:6697

ORF Size (aa)

4848

ORF Size (bp)

4848 bp

RefSeq ID

NM_002335

RefSeq Synonyms

NM_002335, NM_001291902, BC150595,

Species

human

UniGene ID

Hs.6347

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.