human EDEM3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human EDEM3.
shAAV-207561
AAV-h-EDEM3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human EDEM3 (ER degradation enhancing alpha-mannosidase like protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C1orf22
Description (Vector)
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 (PubMed 16431915)).(supplied by OMIM, Mar 2008)
Gene ID
80267
Gene Name (Vector)
ER degradation enhancing alpha-mannosidase like protein 3
Gene Symbol
EDEM3
HGNC ID
HGNC:16787
ORF Size (aa)
2670
ORF Size (bp)
2670 bp
RefSeq ID
NM_025191
RefSeq Synonyms
NM_025191, NM_001319960, BC160020, BC016464,
Species
human
UniGene ID
Hs.523811
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.