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mouse EDEM3 shRNA silencing AAV

Name 
AAV-m-EDEM3-shRNA
Cat No 
shAAV-257755
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Edem3.

shAAV-257755
AAV-m-EDEM3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Edem3 (ER degradation enhancer, mannosidase alpha-like 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310050N11Rik
Description (Vector)
Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes. This process depends on mannose-trimming from the N-glycans. Seems to have alpha 1,2-mannosidase activity (By similarity).
Gene ID
66967
Gene Name (Vector)
ER degradation enhancer, mannosidase alpha-like 3
Gene Symbol
Edem3
ORF Size (aa)
2742
ORF Size (bp)
2742 bp
RefSeq ID
NM_001039644
RefSeq Synonyms
NM_001311166, NM_001311165, NM_001039644, BC145358, BC145357, BC138659, BC138658,
Species
mouse
UniGene ID
Mm.337691

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.