human FOS shRNA Adenovirus
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human FOS gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by qPCR in A549 cells.
1834
Ad-h-FOS-shRNA
Ready-to-use human FOS shRNA Adenovirus. human FOS shRNA adenovirus gene knockdown1834
Gene Reference Data
Alternate Names
AP-1; C-FOS; p55
Description (Vector)
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Gene ID
2353
Gene Name (Vector)
Fos proto-oncogene, AP-1 transcription factor subunit
Gene Symbol
FOS
HGNC ID
HGNC:3796
ORF Size (aa)
1143
RefSeq ID
NM_005252
RefSeq Synonyms
NM_005252, BC004490,
Species
human
UniGene ID
Hs.707896
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.