mouse WWOX Over-expression AAV

Name 
AAV-m-WWOX
Cat No 
AAV-276351
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Wwox.

AAV-276351
AAV-m-WWOX

Ready-to-use AAV expressing Mouse Wwox (WW domain-containing oxidoreductase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5330426P09Rik; 9030416C10Rik; WOX1
Description (Vector)
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Gene ID
80707
Gene Name (Vector)
WW domain-containing oxidoreductase
Gene Symbol
Wwox
ORF Size (aa)
1245
ORF Size (bp)
1245 bp
RefSeq ID
NM_019573
RefSeq Synonyms
NM_019573, BC014716,
Species
mouse
UniGene ID
Mm.440420

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.