mouse WWOX shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Wwox.
shADV-276351
Ad-m-WWOX-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Wwox (WW domain-containing oxidoreductase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5330426P09Rik; 9030416C10Rik; WOX1
Description (Vector)
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Gene ID
80707
Gene Name (Vector)
WW domain-containing oxidoreductase
Gene Symbol
Wwox
ORF Size (aa)
1245
ORF Size (bp)
1245 bp
RefSeq ID
NM_019573
RefSeq Synonyms
NM_019573, BC014716,
Species
mouse
UniGene ID
Mm.440420
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.