mouse VTCN1 Over-expression AAV
This is an AAV expressing Mouse Vtcn1.
AAV-276105
AAV-m-VTCN1
Ready-to-use AAV expressing Mouse Vtcn1 (V-set domain containing T cell activation inhibitor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B7h4; B7s1; B7x; BC032925
Description (Vector)
Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Gene ID
242122
Gene Name (Vector)
V-set domain containing T cell activation inhibitor 1
Gene Symbol
Vtcn1
ORF Size (aa)
852
RefSeq ID
NM_178594
RefSeq Synonyms
NM_178594, BC032925,
Species
mouse
UniGene ID
Mm.137467
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.