mouse TNFRSF21 Over-expression AAV

Name 
AAV-m-TNFRSF21
Cat No 
AAV-274708
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tnfrsf21.

AAV-274708
AAV-m-TNFRSF21

Ready-to-use AAV expressing Mouse Tnfrsf21 (tumor necrosis factor receptor superfamily, member 21). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA959878; DR6; R74815; TR7
Description (Vector)
TNFRSF21 may activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
Gene ID
94185
Gene Name (Vector)
tumor necrosis factor receptor superfamily, member 21
Gene Symbol
Tnfrsf21
ORF Size (aa)
1968
ORF Size (bp)
1968 bp
RefSeq ID
NM_178589
RefSeq Synonyms
NM_178589, BC016420,
Species
mouse
UniGene ID
Mm.200792

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.