mouse TNFRSF21 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Tnfrsf21.
shADV-274708
Ad-m-TNFRSF21-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tnfrsf21 (tumor necrosis factor receptor superfamily, member 21). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA959878; DR6; R74815; TR7
Description (Vector)
TNFRSF21 may activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
Gene ID
94185
Gene Name (Vector)
tumor necrosis factor receptor superfamily, member 21
Gene Symbol
Tnfrsf21
ORF Size (aa)
1968
ORF Size (bp)
1968 bp
RefSeq ID
NM_178589
RefSeq Synonyms
NM_178589, BC016420,
Species
mouse
UniGene ID
Mm.200792
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.