mouse SENP3 Over-expression AAV

Name 
AAV-m-SENP3
Cat No 
AAV-271607
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Senp3.

AAV-271607
AAV-m-SENP3

Ready-to-use AAV expressing Mouse Senp3 (SUMO/sentrin specific peptidase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA408656; Smt3ip; Smt3ip1
Description (Vector)
Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1.
Gene ID
80886
Gene Name (Vector)
SUMO/sentrin specific peptidase 3
Gene Symbol
Senp3
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_030702
RefSeq Synonyms
NM_030702, NM_001163571, BC037014,
Species
mouse
UniGene ID
Mm.284592

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.