mouse SENP3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Senp3.
shAAV-271607
AAV-m-SENP3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Senp3 (SUMO/sentrin specific peptidase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA408656; Smt3ip; Smt3ip1
Description (Vector)
Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1.
Gene ID
80886
Gene Name (Vector)
SUMO/sentrin specific peptidase 3
Gene Symbol
Senp3
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_030702
RefSeq Synonyms
NM_030702, NM_001163571, BC037014,
Species
mouse
UniGene ID
Mm.284592
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.