mouse RGS20 Over-expression AAV

Name 
AAV-m-RGS20
Cat No 
AAV-270489
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Rgs20.

AAV-270489
AAV-m-RGS20

Ready-to-use AAV expressing Mouse Rgs20 (regulator of G-protein signaling 20). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2900073E09Rik; Rgsz1
Description (Vector)
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).
Gene ID
58175
Gene Name (Vector)
regulator of G-protein signaling 20
Gene Symbol
Rgs20
ORF Size (aa)
720
ORF Size (bp)
720 bp
RefSeq ID
NM_021374
RefSeq Synonyms
NM_021374, NM_001290372, NM_001177795, BC116929, BC116925,
Species
mouse
UniGene ID
Mm.103771

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.