mouse DIO1 Over-expression AAV

Name 
AAV-m-DIO1
Cat No 
AAV-257180
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Dio1.

AAV-257180
AAV-m-DIO1

Ready-to-use AAV expressing Mouse Dio1 (deiodinase, iodothyronine, type I). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5DI; D1; ITDI1; TXDI1
Description (Vector)
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.
Gene ID
13370
Gene Name (Vector)
deiodinase, iodothyronine, type I
Gene Symbol
Dio1
ORF Size (aa)
774
RefSeq ID
NM_007860
RefSeq Synonyms
NM_007860, BC089608, BC019786,
Species
mouse
UniGene ID
Mm.148342

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.