mouse DIO1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dio1.
shAAV-257180
AAV-m-DIO1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dio1 (deiodinase, iodothyronine, type I). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5DI; D1; ITDI1; TXDI1
Description (Vector)
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.
Gene ID
13370
Gene Name (Vector)
deiodinase, iodothyronine, type I
Gene Symbol
Dio1
ORF Size (aa)
774
RefSeq ID
NM_007860
RefSeq Synonyms
NM_007860, BC089608, BC019786,
Species
mouse
UniGene ID
Mm.148342
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.