mouse CMPK2 Over-expression AAV

Name 
AAV-m-CMPK2
Cat No 
AAV-255725
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cmpk2.

AAV-255725
AAV-m-CMPK2

Ready-to-use AAV expressing Mouse Cmpk2 (cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1200004E04Rik; TDKI; Tyki
Description (Vector)
CMPK2 may participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs.
Gene ID
22169
Gene Name (Vector)
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
Gene Symbol
Cmpk2
ORF Size (aa)
1263
ORF Size (bp)
1263 bp
RefSeq ID
NM_020557
RefSeq Synonyms
NM_020557, BC057565, BC027329,
Species
mouse
UniGene ID
Mm.271839

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.