mouse CMPK2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cmpk2.
shAAV-255725
AAV-m-CMPK2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cmpk2 (cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1200004E04Rik; TDKI; Tyki
Description (Vector)
CMPK2 may participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs.
Gene ID
22169
Gene Name (Vector)
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
Gene Symbol
Cmpk2
ORF Size (aa)
1263
ORF Size (bp)
1263 bp
RefSeq ID
NM_020557
RefSeq Synonyms
NM_020557, BC057565, BC027329,
Species
mouse
UniGene ID
Mm.271839
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.