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mouse ACOT8 Over-expression AAV

Name 
AAV-m-ACOT8
Cat No 
AAV-251932
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Acot8.

AAV-251932
AAV-m-ACOT8

Ready-to-use AAV expressing Mouse Acot8 (acyl-CoA thioesterase 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PTE-2; Pte1
Description (Vector)
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.
Gene ID
170789
Gene Name (Vector)
acyl-CoA thioesterase 8
Gene Symbol
Acot8
ORF Size (aa)
963
ORF Size (bp)
963 bp
RefSeq ID
NM_133240
RefSeq Synonyms
NM_133240, BC005792,
Species
mouse
UniGene ID
Mm.277878

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.