human YME1L1 Over-expression AAV

Name 
AAV-h-YME1L1
Cat No 
AAV-227979
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human YME1L1.

AAV-227979
AAV-h-YME1L1

Ready-to-use AAV expressing Human YME1L1 (YME1 like 1 ATPase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FTSH; MEG4; PAMP; YME1L
Description (Vector)
YME1L1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
10730
Gene Name (Vector)
YME1 like 1 ATPase
Gene Symbol
YME1L1
HGNC ID
HGNC:12843
ORF Size (aa)
2151
ORF Size (bp)
2151 bp
RefSeq ID
NM_014263
RefSeq Synonyms
NM_139312, NM_014263, NM_001253866, BC024032, BC023507, BC007795,
Species
human
UniGene ID
Hs.499145

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.