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human YME1L1 shRNA silencing Adenovirus

Name 
Ad-h-YME1L1-shRNA
Cat No 
shADV-227979
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human YME1L1.

shADV-227979
Ad-h-YME1L1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human YME1L1 (YME1 like 1 ATPase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FTSH; MEG4; PAMP; YME1L
Description (Vector)
YME1L1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
10730
Gene Name (Vector)
YME1 like 1 ATPase
Gene Symbol
YME1L1
HGNC ID
HGNC:12843
ORF Size (aa)
2151
ORF Size (bp)
2151 bp
RefSeq ID
NM_014263
RefSeq Synonyms
NM_139312, NM_014263, NM_001253866, BC024032, BC023507, BC007795,
Species
human
UniGene ID
Hs.499145

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.