human UBL4A Over-expression AAV

Name 
AAV-h-UBL4A
Cat No 
AAV-227058
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UBL4A.

AAV-227058
AAV-h-UBL4A

Ready-to-use AAV expressing Human UBL4A (ubiquitin like 4A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DX254E; DXS254E; G6PD; GDX; GET5; MDY2; TMA24; ubiquitin-like 4; ubiquitin-like protein 4A; ubiquitin-like protein GDX; UBL4
Description (eCommerce)
Ubiquitin-like 4A (UBL4A) is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P11441].
Gene ID
8266
Gene Name (eCommerce)
ubiquitin like 4A
Gene Name (Vector)
ubiquitin like 4A
Gene Symbol
UBL4A
HGNC ID
HGNC:12505
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
474
ORF Size (bp)
474 bp
Protein Name (eCommerce)
Ubiquitin-like protein 4A
RefSeq ID
NM_014235
RefSeq Synonyms
NM_014235, BC053589, BC043346,
Research Areas
Cell Biology,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Ubiquitin-like 4A (UBL4A) is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P11441].
UniGene ID
Hs.76480
UniProt ID (eCommerce)
P11441

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.