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human UBL4A shRNA silencing Adenovirus

Name 
Ad-h-UBL4A-shRNA
Cat No 
shADV-227058
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human UBL4A.

shADV-227058
Ad-h-UBL4A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human UBL4A (ubiquitin like 4A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DX254E; DXS254E; G6PD; GDX; GET5; MDY2; TMA24; ubiquitin-like 4; ubiquitin-like protein 4A; ubiquitin-like protein GDX; UBL4
Description (eCommerce)
Ubiquitin-like 4A (UBL4A) is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P11441].
Gene ID
8266
Gene Name (eCommerce)
ubiquitin like 4A
Gene Name (Vector)
ubiquitin like 4A
Gene Symbol
UBL4A
HGNC ID
HGNC:12505
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
474
ORF Size (bp)
474 bp
Protein Name (eCommerce)
Ubiquitin-like protein 4A
RefSeq ID
NM_014235
RefSeq Synonyms
NM_014235, BC053589, BC043346,
Research Areas
Cell Biology,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Ubiquitin-like 4A (UBL4A) is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P11441].
UniGene ID
Hs.76480
UniProt ID (eCommerce)
P11441

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.