human TSSC4 Over-expression AAV

Name
AAV-h-TSSC4

Cat No
AAV-226667

Availability
4-5 weeks

This is an AAV expressing Human TSSC4.

AAV-226667

AAV-h-TSSC4

Ready-to-use AAV expressing Human TSSC4 (tumor suppressing subtransferable candidate 4). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

TSSC4 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. TSSC4 is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. TSSC4 may play a role in malignancies and disease that involve this region.

Gene ID

10078

Gene Name (Vector)

tumor suppressing subtransferable candidate 4

Gene Symbol

TSSC4

HGNC ID

HGNC:12386

ORF Size (aa)

798

RefSeq ID

NM_005706

RefSeq Synonyms

NM_005706, NM_001297661, NM_001297660, NM_001297659, NM_001297658, BC050616, BC006091,

Species

human

UniGene ID

Hs.523424

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.