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human TSSC4 shRNA silencing Adenovirus

Name 
Ad-h-TSSC4-shRNA
Cat No 
shADV-226667
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human TSSC4.

shADV-226667
Ad-h-TSSC4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TSSC4 (tumor suppressing subtransferable candidate 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
TSSC4 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. TSSC4 is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. TSSC4 may play a role in malignancies and disease that involve this region.
Gene ID
10078
Gene Name (Vector)
tumor suppressing subtransferable candidate 4
Gene Symbol
TSSC4
HGNC ID
HGNC:12386
ORF Size (aa)
798
RefSeq ID
NM_005706
RefSeq Synonyms
NM_005706, NM_001297661, NM_001297660, NM_001297659, NM_001297658, BC050616, BC006091,
Species
human
UniGene ID
Hs.523424

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.