human TMUB1 Over-expression AAV

Name 
AAV-h-TMUB1
Cat No 
AAV-226044
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TMUB1.

AAV-226044
AAV-h-TMUB1

Ready-to-use AAV expressing Human TMUB1 (transmembrane and ubiquitin like domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C7orf21; dendritic cell-derived ubiquitin-like protein; DULP; hepatocyte odd protein shuttling protein; SB144; transmembrane and ubiquitin-like domain-containing protein 1; ubiquitin-like protein DULP; ubiquitin-like protein SB144
Description (eCommerce)
Transmembrane and ubiquitin-like domain-containing protein 1 (TMUB1) is involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR (PubMed:21343306). It is involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity) and acts as negative regulator of hepatocyte growth during regeneration (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BVT8].
Gene ID
83590
Gene Name (eCommerce)
transmembrane and ubiquitin like domain containing 1
Gene Name (Vector)
transmembrane and ubiquitin like domain containing 1
Gene Symbol
TMUB1
HGNC ID
HGNC:21709
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
741
ORF Size (bp)
741 bp
Protein Name (eCommerce)
Transmembrane and ubiquitin-like domain-containing protein 1
RefSeq ID
NM_031434
RefSeq Synonyms
NM_031434, NM_001136044, BC033182, BC000936,
Research Areas
Cell Biology,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Transmembrane and ubiquitin-like domain-containing protein 1 (TMUB1) is involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR (PubMed:21343306). It is involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity) and acts as negative regulator of hepatocyte growth during regeneration (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BVT8].
UniGene ID
Hs.647096
UniProt ID (eCommerce)
Q9BVT8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.