human TFR2 Over-expression AAV

Name 
AAV-h-TFR2
Cat No 
AAV-225373
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TFR2.

AAV-225373
AAV-h-TFR2

Ready-to-use AAV expressing Human TFR2 (transferrin receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HFE3; TFRC2
Description (Vector)
TFR2 encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
7036
Gene Name (Vector)
transferrin receptor 2
Gene Symbol
TFR2
HGNC ID
HGNC:11762
ORF Size (aa)
2406
ORF Size (bp)
2406 bp
RefSeq ID
NM_003227
RefSeq Synonyms
NM_003227, NM_001206855, BC142630,
Species
human
UniGene ID
Hs.544932

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.